Just breathe: a review of sex and gender in chronic lung disease.

ABSTRACT: Chronic lung diseases are the third leading cause of death worldwide and are increasing in prevalence over time. Although much of our traditional understanding of health and disease is derived from study of the male of the species - be it animal or human - there is increasing evidence that sex and gender contribute to differences in disease risk, prevalence, presentation, severity, treatment approach, response and outcomes. Chronic obstructive pulmonary disease, asthma and bronchiectasis represent the most prevalent and studied chronic lung diseases and have key sex- and gender-based differences which are critical to consider and incorporate into clinical and research approaches. Mechanistic differences present opportunities for therapeutic development whereas behavioural and clinical diff

SUBMITTER: Somayaji R 

PROVIDER: S-EPMC9488531 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature