Learning from registries in pulmonary arterial hypertension: pitfalls and recommendations.

ABSTRACT: Pulmonary arterial hypertension is a rare and incurable chronic disease characterised by a progressive increase in pulmonary vascular resistance and right heart failure. Patient registries collecting observational data can be of great value in the understanding of clinical problems. While clinical trials provide data in selected patient populations, registries better depict real-life practice. This review aims to reflect the input of patient registries in the general knowledge of the disease. Advances in epidemiology of the different subgroups, including data on incidence and/or prevalence, increasing age at presentation and stagnating diagnostic delay are reported. The importance of haemodynamic definition criteria and cardiac comorbidities are underscored. The review also shows the major

SUBMITTER: Swinnen K 

PROVIDER: S-EPMC9488628 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature