Personalised medicine in asthma: from curative to preventive medicine.

ABSTRACT: The concept of asthma has changed substantially in recent years. Asthma is now recognised as a heterogeneous entity that is complex to treat. The subdivision of asthma, provided by "cluster" analyses, has revealed various groups of asthma patients who share phenotypic features. These phenotypes underlie the need for personalised asthma therapy because, in contrast to the previous approach, treatment must be tailored to the individual patient. Determination of the patient's asthma phenotype is therefore essential but sometimes challenging, particularly in elderly patients with a multitude of comorbidities and a complex exposure history. This review first describes the various asthma phenotypes, some of which were defined empirically and others through cluster analysis, and then discusses pe

SUBMITTER: Guilleminault L 

PROVIDER: S-EPMC9489193 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature