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Capturing the pool dilution effect in group testing regression: A Bayesian approach.


ABSTRACT: Group (pooled) testing is becoming a popular strategy for screening large populations for infectious diseases. This popularity is owed to the cost savings that can be realized through implementing group testing methods. These methods involve physically combining biomaterial (eg, saliva, blood, urine) collected on individuals into pooled specimens which are tested for an infection of interest. Through testing these pooled specimens, group testing methods reduce the cost of diagnosing all individuals under study by reducing the number of tests performed. Even though group testing offers substantial cost reductions, some practitioners are hesitant to adopt group testing methods due to the so-called dilution effect. The dilution effect describes the phenomenon in which biomaterial from negativ

SUBMITTER: Self S 

PROVIDER: S-EPMC9489666 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature