Smart soft contact lenses for continuous 24-hour monitoring of intraocular pressure in glaucoma care.

ABSTRACT: Continuous monitoring of intraocular pressure, particularly during sleep, remains a grand challenge in glaucoma care. Here we introduce a class of smart soft contact lenses, enabling the continuous 24-hour monitoring of intraocular pressure, even during sleep. Uniquely, the smart soft contact lenses are built upon various commercial brands of soft contact lenses without altering their intrinsic properties such as lens power, biocompatibility, softness, transparency, wettability, oxygen transmissibility, and overnight wearability. We show that the smart soft contact lenses can seamlessly fit across different corneal curvatures and thicknesses in human eyes and therefore accurately measure absolute intraocular pressure under ambulatory conditions. We perform a comprehensive set of in vivo ev

SUBMITTER: Zhang J 

PROVIDER: S-EPMC9489713 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature