Proton-mediated photoprotection mechanism in photosystem II.

ABSTRACT: Photo-induced charge separation, which is terminated by electron transfer from the primary quinone Q_A to the secondary quinone Q_B, provides the driving force for O₂ evolution in photosystem II (PSII). However, the backward charge recombination using the same electron-transfer pathway leads to the triplet chlorophyll formation, generating harmful singlet-oxygen species. Here, we investigated the molecular mechanism of proton-mediated Q_A ^⋅- stabilization. Quantum mechanical/molecular mechanical (QM/MM) calculations show that in response to the loss of the bicarbonate ligand, a low-barrier H-bond forms between D2-His214 and Q_A ^⋅-. The migration of the proton from D2-His214 toward Q_A ^⋅- stabilize

SUBMITTER: Sugo Y 

PROVIDER: S-EPMC9490181 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature