Extraction of flavonoids from Citri Reticulatae Pericarpium Viride using a deep eutectic solvent.

ABSTRACT: Flavonoids are the main active ingredient in Citri Reticulatae Pericarpium Viride (CRPV). In this study, a deep eutectic solvent (DES) was explored to extract the main flavonoids from CRPV, including narirutin (NAR) and hesperidin (HES). A total of 30 DESs were prepared, and DES-20 (proline : urea) was selected as the optimal solvent. According to the single factor and response surface methodology experiments, the optimal extraction conditions for the flavonoids included a molar ratio of 1 : 2, water content of 30%, extraction time of 28 min, extraction power of 240 W, and a liquid-to-solid ratio of 70 mL g^-1 and the optimal extraction yields of NAR and HES were 21 ± 2 mg g^-1 and 60 ± 2 mg g^-1, respectively. The recovery rate of NAR and HES with macr

SUBMITTER: Li G 

PROVIDER: S-EPMC9490517 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature