Modifiable risk factors and long term risk of type 2 diabetes among individuals with a history of gestational diabetes mellitus: prospective cohort study.

ABSTRACT:

Objectives

To evaluate the individual and combined associations of five modifiable risk factors with risk of type 2 diabetes among women with a history of gestational diabetes mellitus and examine whether these associations differ by obesity and genetic predisposition to type 2 diabetes.

Design

Prospective cohort study.

Setting

Nurses' Health Study II, US.

Participants

4275 women with a history of gestational diabetes mellitus, with repeated measurements of weight and lifestyle factors and followed up between 1991 and 2009.

Main outcome measure

Self-reported, clinically diagnosed type 2 diabetes. Five modifiable risk factors were assessed, including not being overweight or obese (body mass index <25.0), high quality diet (top two fifthsof the modified Al

SUBMITTER: Yang J 

PROVIDER: S-EPMC9490550 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature