External validation of the ProVent score for prognostication of 1-year mortality of critically ill patients with prolonged mechanical ventilation: a single-centre, retrospective observational study in Austria.

ABSTRACT:

Objectives

In critically ill patients requiring mechanical ventilation for at least 21 days, 1-year mortality can be estimated using the ProVent score, calculated from four variables (age, platelet count, vasopressor use and renal replacement therapy). We aimed to externally validate discrimination and calibration of the ProVent score and, if necessary, to update its underlying regression model.

Design

Retrospective, observational, single-centre study.

Setting

11 intensive care units at one tertiary academic hospital.

Patients

780 critically ill adult patients receiving invasive mechanical ventilation for at least 21 days.

Primary outcome measure

1-year mortality after intensive care unit discharge.

Results

380 patients (49%) had died after 1 year

SUBMITTER: Dibiasi C 

PROVIDER: S-EPMC9490575 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature