Height outcomes in Korean children with idiopathic short stature receiving growth hormone treatment.

ABSTRACT:

Objectives

Growth hormone (GH) therapy's capacity to increase height velocity and height at the end of the study in children with idiopathic short stature (ISS) is controversial. We aimed to investigate the height standard deviation score (SDS) and height velocity of patients with ISS in Korea who received GH treatment.

Methods

We retrospectively reviewed and performed linear mixed model and survival analyses on data from 12 tertiary hospitals in Korea, including subjects diagnosed with ISS from January 2009 to September 2019, treated with GH therapy for more than 6 months, and who were at a pre-pubertal state at the time of diagnosis.

Results

We included 578 children (330 boys and 248 girls). The mean daily dose of GH in this study was 0.051 mg/kg, which was lower th

SUBMITTER: Chae HW 

PROVIDER: S-EPMC9490583 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature