Clinical characteristics of ocular myasthenia gravis and outcomes of secondary generalisation: a systematic review protocol.

ABSTRACT:

Objective

We aim to systematically assess the clinical characteristics of ocular myasthenia gravis (OMG) and report on the proportion of patients who develop secondary generalised myasthenia gravis (SGMG).

Introduction

OMG is an autoimmune neuromuscular junction disorder resulting in ptosis and diplopia. A proportion of patients with OMG develop weakness in their limbs, respiratory or bulbar muscles, that is, convert to SGMG. The proportion of patients converting to SGMG reported in the literature have been varied. We therefore aim to systematically assess the clinical characteristics of OMG and outcomes of SGMG reported in the literature to date.

Inclusion criteria

Studies describing a population of adults with OMG, that is, MG with ocular symptoms and signs only, se

SUBMITTER: Fang CEH 

PROVIDER: S-EPMC9490595 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature