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Synthesis of Tunable Fluorescent Imidazole-Fused Heterocycle Dimers.

ABSTRACT: A short, concise, and one-pot synthesis of imidazo-fused heterocycle dimers with tunable fluorescent properties has been developed. By the first time use of glyoxal dimethyl acetal in the Groebke-Blackburn-Bienaymé (GBB) three-component reaction (3CR), the innovation features a new series of fluorescence-tunable imidazo-fused heterocycle dimers exhibiting a broad substrate scope with good yields. Luminescence studies demonstrate that these GBB-dimers possess color-tunable properties, and their emission colors can be successively changed from blue to green and yellow by easy substituent control.

SUBMITTER: Zheng Q

PROVIDER: S-EPMC9490819 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature

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Synthesis of Tunable Fluorescent Imidazole-Fused Heterocycle Dimers.

Zheng Qiang Q Li Xin X Kurpiewska Katarzyna K Dömling Alexander A

Organic letters 20220713 28

A short, concise, and one-pot synthesis of imidazo-fused heterocycle dimers with tunable fluorescent properties has been developed. By the first time use of glyoxal dimethyl acetal in the Groebke-Blackburn-Bienaymé (GBB) three-component reaction (3CR), the innovation features a new series of fluorescence-tunable imidazo-fused heterocycle dimers exhibiting a broad substrate scope with good yields. Luminescence studies demonstrate that these GBB-dimers possess color-tunable properties, and their e ...[more]

PMID: 35830622

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