High-resolution, 3D multi-TE ¹ H MRSI using fast spatiospectral encoding and subspace imaging.

ABSTRACT:

Purpose

To develop a novel method to achieve fast, high-resolution, 3D multi-TE ¹ H-MRSI of the brain.

Methods

A new multi-TE MRSI acquisition strategy was developed that integrates slab selective excitation with adiabatic refocusing for better volume coverage, rapid spatiospectral encoding, sparse multi-TE sampling, and interleaved water navigators for field mapping and calibration. Special data processing strategies were developed to interpolate the sparsely sampled data, remove nuisance signals, and reconstruct multi-TE spatiospectral distributions with high SNR. Phantom and in vivo experiments have been carried out to demonstrate the capability of the proposed method.

Results

The proposed acquisition can produce multi-TE ¹ H-MRSI data with th

SUBMITTER: Wang Z 

PROVIDER: S-EPMC9491015 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature