Brain connectivity at rest predicts individual differences in normative activity during movie watching.

ABSTRACT: When exposed to the same sensory event, some individuals are bound to have less typical experiences than others. Previous research has investigated this phenomenon by showing that the typicality of one's sensory experience is associated with the typicality of their stimulus-evoked brain activity (as measured by intersubject correlation, or ISC). Individual differences in ISC have recently been attributed to variability in focal neural processing. However, the extent to which these differences reflect purely intra-regional variability versus variation in the brain's baseline ability to transmit information between regions has yet to be established. Here, we show that an individual's degree and spatial distribution of ISC are closely related to their brain's functional organization at rest.

SUBMITTER: Gruskin DC 

PROVIDER: S-EPMC9491116 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature