Photocatalyst-free hydroacylations of electron-poor alkenes and enones under visible-light irradiation.

ABSTRACT: Herein we present a photocatalyst- and additive-free radical hydroacylation of electron-poor double bonds under mild reaction conditions. Using 4-acyl-Hantzsch ester radical reservoirs, various Michael acceptors, enones and para-quinone methide substrates could be used. The protocol enabled further derivatizations and it could also be extended to a few unactivated alkenes. Moreover, the nature of the radical process was also investigated.

SUBMITTER: Palvolgyi AM 

PROVIDER: S-EPMC9491158 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature