Palladium-catalysed C-H arylation of benzophospholes with aryl halides.

ABSTRACT: A palladium-catalysed C-H arylation of benzophospholes with aryl halides has been developed. The reaction with aryl iodides and bromides proceeds well even under phosphine ligand-free Pd(OAc)₂ catalysis whereas the Pd(PCy₃)₂ is effective for the coupling with less reactive aryl chlorides. The optimal conditions are also applicable to the double arylations with organic dihalides and annulation reaction with ortho-dihalogenated benzenes, making the corresponding benzophosphole-based acceptor-donor-acceptor-type molecules and highly condensed heteroacene-type molecules of potent interest in materials chemistry. Although there are many reports of catalytic C-H functionalisations of related benzoheteroles such as indoles, benzothiophenes, and benzofurans,

SUBMITTER: Xu S 

PROVIDER: S-EPMC9491221 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature