Neurological manifestations in thrombotic microangiopathy: Imaging features, risk factors and clinical course.

ABSTRACT:

Background and purpose

Thrombotic microangiopathy (TMA) is a group of microvascular occlusive disorders that presents with neurological involvement in up to 87% of the cases. Although the central nervous system (CNS) is an important target organ in TMA, the role of neurological manifestations in the disease clinical course is not well established. In this study, we described the neurological manifestations and CNS radiological aspects in patients with a first, acute TMA event. We also examined the association between severe neurological involvement and adverse clinical outcomes in TMA.

Methods

A cohort of patients diagnosed with a first TMA event between 1995 and 2016 was included, their medical charts and imaging tests were retrospectively evaluated.

Results

A total

SUBMITTER: de Castro JTS 

PROVIDER: S-EPMC9491546 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature