Association between cortisol and aging-related hippocampus volume changes in community-dwelling older adults: a 7-year follow-up study.

ABSTRACT:

Background

Identifying peripheral biomarkers related to modifiable risk factors to prevent dementia at an early stage will be extremely beneficial. We have been studying how older adults can maintain their mental health and continue to live in a familiar community. The aim of this study is to investigate the association between serum cortisol levels and brain volume among older adults in rural Japan.

Methods

This was a longitudinal study conducted in Kurokawa-cho, Imari, Saga Prefecture, Japan, among people aged 65 years and above, as reported previously. We conducted a survey twice. The first survey was conducted from October 2009 to March 2011 (Timepoint 1) and the second was conducted from November 2016 to September 2017 (Timepoint 2). Blood samples for serum cortisol lev

SUBMITTER: Orihashi R 

PROVIDER: S-EPMC9491648 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature