Relationships between intrauterine fetal growth trajectories and markers of adiposity and inflammation in young adults.

ABSTRACT:

Background

There is now good evidence that events during gestation significantly influence the developmental well-being of an individual in later life. This study aimed to investigate the relationships between intrauterine growth trajectories determined by serial ultrasound and subsequent markers of adiposity and inflammation in the 27-year-old adult offspring from the Raine Study, an Australian longitudinal pregnancy cohort.

Methods

Ultrasound fetal biometric measurements including abdominal circumference (AC), femur length (FL), and head circumference (HC) from 1333 mother-fetal pairs (Gen1-Gen2) in the Raine Study were used to develop fetal growth trajectories using group-based trajectory modeling. Linear mixed modeling investigated the relationship between adult body mas

SUBMITTER: Yadav A 

PROVIDER: S-EPMC9492546 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature