Clinicopathological Characteristics Predicting Further Recurrence and Survival Following Resection of In-Transit Melanoma Metastases.

ABSTRACT:

Background

In-transit metastases (ITMs) affect approximately 4% of patients with cutaneous melanoma. This study sought to identify clinical and pathological characteristics that predict further recurrence and survival following resection of ITMs.

Patients and methods

Patients (n = 573) who underwent surgical resection of their first presentation of ITM following previous surgical treatment of an American Joint Committee on Cancer (AJCC) stage I-II melanoma between 1969 and 2017 were identified from an institutional database. Clinicopathological predictors of patterns of recurrence and survival following ITM resection were sought.

Results

The median time of ITM development was 2.4 years after primary melanoma resection. ITMs were most frequently located on the lower li

SUBMITTER: Lawless AK 

PROVIDER: S-EPMC9492704 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature