Unraveling the potential of endothelial progenitor cells as a treatment following ischemic stroke.

ABSTRACT: Ischemic stroke is becoming one of the most common causes of death and disability in developed countries. Since current therapeutic options are quite limited, focused on acute reperfusion therapies that are hampered by a very narrow therapeutic time window, it is essential to discover novel treatments that not only stop the progression of the ischemic cascade during the acute phase, but also improve the recovery of stroke patients during the sub-acute or chronic phase. In this regard, several studies have shown that endothelial progenitor cells (EPCs) can repair damaged vessels as well as generate new ones following cerebrovascular damage. EPCs are circulating cells with characteristics of both endothelial cells and adult stem cells presenting the ability to differentiate into mature endot

SUBMITTER: Custodia A 

PROVIDER: S-EPMC9492921 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature