Immune-modulatory effect of human milk in reducing the risk of Kawasaki disease: A nationwide study in Korea.

ABSTRACT:

Background

Kawasaki disease (KD) is the most common acquired heart disease among children in developed countries, but the etiology is still unclear. There are several hypotheses regarding the outbreak of KD, including infection, genetics, and immunity. Since breastfeeding plays an essential role in the immune system's composition, investigating breastfeeding's effects on the occurrence of KD would be an excellent way to identify the etiology of KD.

Aim

To determine whether the incidence of KD decreases with breastfeeding.

Methods

This nationwide cohort study analyzed data from the National Health Insurance Service (NHIS) in South Korea and included 1,910,438 infants who underwent their first National Children's Health Examination (NCHE) between 2008 and 2014. Feeding

SUBMITTER: Na JY 

PROVIDER: S-EPMC9492926 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature