Municipal and neighbourhood level wastewater surveillance and subtyping of an influenza virus outbreak.

ABSTRACT: Recurrent influenza epidemics and pandemic potential are significant risks to global health. Public health authorities use clinical surveillance to locate and monitor influenza and influenza-like cases and outbreaks to mitigate hospitalizations and deaths. Currently, global integration of clinical surveillance is the only reliable method for reporting influenza types and subtypes to warn of emergent pandemic strains. The utility of wastewater surveillance (WWS) during the COVID-19 pandemic as a less resource intensive replacement or complement for clinical surveillance has been predicated on analyzing viral fragments in wastewater. We show here that influenza virus targets are stable in wastewater and partitions favorably to the solids fraction. By quantifying, typing, and subtyping the vi

SUBMITTER: Mercier E 

PROVIDER: S-EPMC9493155 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature