Prognostic value of plasma adipokine chemerin in patients with coronary artery disease.

ABSTRACT:

Background

Adipokine chemerin was proven to be associated with coronary artery disease (CAD), but its prognostic implications in CAD remain unclear.

Methods

This study consists of two parts, one is a basic study and the other is a clinical cohort study. First, we investigated the differential expression of six adipokines in the atherosclerotic mice model compared to mice with milder degrees of atherosclerosis and mice without atherosclerosis using microarray data. We then examined the potential of chemerin as a diagnostic and prognostic indicator in a CAD cohort. A total of 152 patients were enrolled in our study, including 77 patients with angiographically proven CAD and 75 control subjects without cardiovascular disease. Plasma adipokine chemerin levels were measured in al

SUBMITTER: Wang B 

PROVIDER: S-EPMC9493186 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature