Comparison of Severity of Genitourinary Syndrome of Menopause Symptoms After Carbon Dioxide Laser vs Vaginal Estrogen Therapy: A Systematic Review and Meta-analysis.

ABSTRACT:

Importance

Vaginal estrogen for genitourinary syndrome of menopause (GSM) should be used with caution in women with contraindications, highlighting the need for effective treatment alternatives.

Objective

To compare the severity of GSM after vaginal laser vs estrogen therapy.

Data sources

The PubMed, Embase, and Cochrane Library databases were searched for articles published from database inception to April 8, 2022, with no language restrictions. Reference lists were also searched.

Study selection

Randomized clinical trials (RCTs) that compared the use of lasers with vaginal estrogen in adults were selected.

Data extraction and synthesis

Two investigators independently extracted data from included studies. The Cochrane risk of bias tool for RCTs was used

SUBMITTER: Jang YC 

PROVIDER: S-EPMC9494191 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature