Ontology highlight
ABSTRACT:
SUBMITTER: Vadaq N
PROVIDER: S-EPMC9494231 | biostudies-literature | 2022 Oct
REPOSITORIES: biostudies-literature
Vadaq Nadira N van de Wijer Lisa L van Eekeren Louise E LE Koenen Hans H de Mast Quirijn Q Joosten Leo A B LAB Netea Mihai G MG Matzaraki Vasiliki V van der Ven André J A M AJAM
iScience 20220907 10
Despite antiretroviral therapy (ART), people living with HIV (PLHIV) display persistent inflammation leading to non-AIDS-related co-morbidities. To better understand underlying mechanisms, we compared targeted plasma inflammatory protein concentration (n = 92) between a cohort of 192 virally suppressed PLHIV, who were followed-up for five years, and 416 healthy controls (HC). Findings were validated in an independent cohort of 649 virally suppressed PLHIV and 98 HC. Compared to HC, PLHIV exhibit ...[more]