Antiresorptive treatments for corticosteroid-induced osteoporosis: a Bayesian network meta-analysis.

ABSTRACT:

Introduction

Corticosteroid-induced osteoporosis (CIO) is the most common type of secondary osteoporosis, leading to fractures, and increased morbidity and mortality.

Source of data

Pubmed, EMBASE, Scopus and Google Scholar databases.

Areas of agreement

Prolonged glucocorticoids administration leads to secondary osteoporosis.

Areas of controversy

The optimal management for CIO is controversial.

Growing points

The present study compared bone mineral density, fractures and adverse events in patients undergoing treatment with risedronate, alendronate, zoledronate, denosumab or etidronate for CIO.

Areas timely for developing research

For selected patients with CIO, alendronate performed better overall. These results must be interpreted within the limi

SUBMITTER: Migliorini F 

PROVIDER: S-EPMC9494254 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature