A deeper insight into the sialome of male and female Ochlerotatus triseriatus mosquitoes.

ABSTRACT: Over the last 20 years, advancements in sequencing technologies have highlighted the unique composition of the salivary glands of blood-feeding arthropods. Further biochemical and structural data demonstrated that salivary proteins can disrupt host hemostasis, inflammation and immunity, which favors pathogen transmission. Previously, a Sanger-based sialome of adult Ochlerotatus triseriatus female salivary glands was published based on 731 expressed sequence tag (ESTs). Here, we revisited O. triseriatus salivary gland contents using an Illumina-based sequencing approach of both male and female tissues. In the current data set, we report 10,317 DNA coding sequences classified into several functional classes. The translated transcripts also served as a reference database for proteomic analysi

SUBMITTER: Lu S 

PROVIDER: S-EPMC9494274 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature