Pregnancy status at the time of COVID-19 vaccination and incidence of SARS-CoV-2 infection.

ABSTRACT:

Background

Pregnant women are recommended to receive COVID-19 vaccines; however, relative effectiveness of vaccination by pregnancy status is unclear.

Methods

We compared the relative effectiveness of mRNA COVID-19 vaccines according to whether women received both while pregnant (n= 7,412), one dose while pregnant (n = 3,538), both while postpartum (n = 1,856), or both doses while neither pregnant nor postpartum (n = 6,687). We estimated risk of SARS-CoV-2 infection starting 14 days after the second dose using Cox regression, reporting hazard ratios (HR) and 95% confidence intervals (CI). Secondly, we examined relative effectiveness of a third (booster) dose while pregnant compared to outside pregnancy. The major circulating variant during the study period was the Delta vari

SUBMITTER: Magnus MC 

PROVIDER: S-EPMC9494391 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature