Concussion in Non-athletes: Assessment of Cognition and Symptomatology (CONTACTS) study protocol - an exploratory cohort study investigating the utility of sports concussion assessment tools and salivary microRNAs to diagnose concussion in NHS patients.

ABSTRACT:

Introduction

Concussion is a complex pathophysiological process with a wide range of non-specific signs and symptoms. There are currently no objective diagnostic tests to identify concussion, and diagnosis relies solely on history and examination. Recent research has identified a unique panel of microRNAs (miRNAs) that distinguish between concussed and non-concussed rugby players. This study aims to assess the diagnostic utility of salivary miRNAs in concussion for a sample of UK National Health Service patients and whether well-established sports-related concussion (SRC) assessment tools may be translated into the emergency department (ED).

Methods and analysis

Concussion in Non-athletes: Assessment of Cognition and Symptomatology is a single-centre, prospective, two-phase

SUBMITTER: Toman E 

PROVIDER: S-EPMC9494594 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature