Long-Term Exposure to Ambient Fine Particulate Matter and Incidence of Major Cardiovascular Diseases: A Prospective Study of 0.5 Million Adults in China.

ABSTRACT: Few cohort studies explored the long-term effects of ambient fine particulate matter (PM_2.5) on incidence of cardiovascular diseases (CVDs), especially in countries with higher levels of air pollution. We aimed to evaluate the association between long-term exposure to PM_2.5 and incidence of CVD in China. We performed a prospective cohort study in ten regions that recruited 512,689 adults during 2004-2008, with follow-up until 2017. Annual PM_2.5 concentrations were estimated using a satellite-based model with national coverage and 1 x 1 km spatial resolution. Time-varying Cox proportional hazard regression models were used to estimate hazard ratios (HRs) for all-cause and cause-specific CVDs associated with PM_2.5, adjusting for conventional covari

SUBMITTER: Liu C 

PROVIDER: S-EPMC9494741 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature