Clinical factors associated with cerebral autoregulation in ischemic stroke related to small artery occlusion.

ABSTRACT:

Background

Existing data suggest that cerebral autoregulation (CA) varies among different subtypes of ischaemic stroke. CA is globally impaired in patients with small artery occlusion (SAO). However, the factors influencing CA impairment in patients remains to be elucidated.

Methods

Stroke patients with SAO who underwent brain magnetic resonance imaging (MRI) were prospectively studied. Within 7 days after stroke onset, CA was recorded from the middle cerebral artery blood flow velocity and arterial blood pressure was simultaneously measured. Transfer function analysis was used to derive CA parameters, including gain and phase. Clinical characteristics, mean arterial pressure (MAP), biochemical findings, and cerebral small vessel disease (CSVD) markers on MRI were assessed i

SUBMITTER: Wu X 

PROVIDER: S-EPMC9494772 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature