Osteotropic Effect of Parenteral Obesity in Programmed Male Rats Fed a Calorically Differentiated Diet during Growth and Development.

ABSTRACT: The experiment was undertaken to assess whether the continuation or change of the parents' diet affects the previously programmed bone metabolism of the male offspring during its growth and development. A total of 16 male and 32 female Wistar rats were divided into groups and fed a standard (diet S) or high-energy (diet F). After the induction of obesity, the rats from groups S and F, as the parent generation, were used to obtain male offspring, which were kept with their mothers until the weaning day (21 days of age). In our earlier study, we documented the programming effects of the diet used in parents on the skeletal system of offspring measured on the weaning day. Weaned male offspring constitute one control group-parents and offspring fed the S diet. There were three experimental gro

SUBMITTER: Radzki RP 

PROVIDER: S-EPMC9495023 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature