Hardware-in-Loop Comparison of Physiological Closed-Loop Controllers for the Autonomous Management of Hypotension.

ABSTRACT: Trauma and hemorrhage are leading causes of death and disability worldwide in both civilian and military contexts. The delivery of life-saving goal-directed fluid resuscitation can be difficult to provide in resource-constrained settings, such as in forward military positions or mass-casualty scenarios. Automated solutions for fluid resuscitation could bridge resource gaps in these austere settings. While multiple physiological closed-loop controllers for the management of hypotension have been proposed, to date there is no consensus on controller design. Here, we compare the performance of four controller types-decision table, single-input fuzzy logic, dual-input fuzzy logic, and proportional-integral-derivative using a previously developed hardware-in-loop test platform where a range of

SUBMITTER: Snider EJ 

PROVIDER: S-EPMC9495383 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature