Blood parameters and pathological lesions in pigs experimentally infected with Vietnam's first isolated African swine fever virus.

ABSTRACT: African swine fever virus (ASFV) is a notable virus and one of the most serious global threats to the pig industry. Improving awareness about host-virus interactions could facilitate the understanding of the disease pathogenesis. Therefore, we investigated changes in blood parameters, viral loads, and pathological changes in ASFV-inoculated pigs according to the time of death after the onset of viremia. For the analyses, the ASFV-infected pigs (n = 10) were divided into two groups (five pigs/group) according to their time of death after the onset of viremia. The blood cell count dynamics and serum biochemistry profiles were similar between the groups; however, viral load distribution was different. A comparison of the histopathological changes and immunohistochemistry results betwee

SUBMITTER: Oh SI 

PROVIDER: S-EPMC9495444 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature