Genome-Based Analysis of Verticillium Polyketide Synthase Gene Clusters.

ABSTRACT: Polyketides are structurally diverse and physiologically active secondary metabolites produced by many organisms, including fungi. The biosynthesis of polyketides from acyl-CoA thioesters is catalyzed by polyketide synthases, PKSs. Polyketides play roles including in cell protection against oxidative stress, non-constitutive (toxic) roles in cell membranes, and promoting the survival of the host organisms. The genus Verticillium comprises many species that affect a wide range of organisms including plants, insects, and other fungi. Many are known as causal agents of Verticillium wilt diseases in plants. In this study, a comparative genomics approach involving several Verticillium species led us to evaluate the potential of Verticillium species for producing poly

SUBMITTER: Sayari M 

PROVIDER: S-EPMC9495618 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature