Evaluation of Hepatic Detoxification Effects of Enteromorpha prolifera Polysaccharides against Aflatoxin B₁ in Broiler Chickens.

ABSTRACT: Aflatoxin B₁ (AFB₁) is a major risk factor in animal feed. Seaweed (Enteromorpha prolifera)-derived polysaccharides (SDP) are natural antioxidants with multiple biological functions, which may have an in vivo detoxification effect on AFB₁. The current study aimed to evaluate whether SDP could mitigate AFB₁-induced hepatotoxicity in broilers. A total of 216 chickens (male, 5 weeks old) were randomly allocated to three groups with differing feeding patterns, lasting 4 weeks: (1) control group (CON, fed a basal diet); (2) AFB₁ group (fed a basal diet mixed with 0.1 mg/kg AFB₁); and (3) AFB₁ + SDP group (AFB₁ group + 0.25% SDP). The results showed that dietary SDP improved the liver function-related

SUBMITTER: Liu WC 

PROVIDER: S-EPMC9495745 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature