A Ratiometric Organic Fluorescent Nanogel Thermometer for Highly Sensitive Temperature Sensing.

ABSTRACT: Sensing temperature in biological systems is of great importance, as it is constructive to understanding various physiological and pathological processes. However, the realization of highly sensitive temperature sensing with organic fluorescent nanothermometers remains challenging. In this study, we report a ratiometric fluorescent nanogel thermometer and study its application in the determination of bactericidal temperature. The nanogel is composed of a polarity-sensitive aggregation-induced emission luminogen with dual emissions, a thermoresponsive polymer with a phase transition function, and an ionic surface with net positive charges. During temperature-induced phase transition, the nanogel exhibits a reversible and sensitive spectral change between a red-emissive state and a blue-emis

SUBMITTER: Wang C 

PROVIDER: S-EPMC9496083 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature