Ontology highlight
ABSTRACT:
SUBMITTER: Kovtun AS
PROVIDER: S-EPMC9496097 | biostudies-literature | 2022 Sep
REPOSITORIES: biostudies-literature
Kovtun Alexey S AS Averina Olga V OV Angelova Irina Y IY Yunes Roman A RA Zorkina Yana A YA Morozova Anna Y AY Pavlichenko Alexey V AV Syunyakov Timur S TS Karpenko Olga A OA Kostyuk George P GP Danilenko Valery N VN
Biomedicines 20220902 9
Major depressive disorder (MDD) is among the most prevalent mental disorders worldwide. Factors causing the pathogenesis of MDD include gut microbiota (GM), which interacts with the host through the gut-brain axis. In previous studies of GM in MDD patients, 16S rRNA sequencing was used, which provided information about composition but not about function. In our study, we analyzed whole metagenome sequencing data to assess changes in both the composition and functional profile of GM. We looked at ...[more]