Contralesional Cortical and Network Features Associated with Preoperative Language Deficit in Glioma Patients.

ABSTRACT: Lower-grade Gliomas anchored in eloquent areas cause varying degrees of language impairment. Except for a tumor's features, contralesional compensation may explain these differences. Therefore, studying changes in the contralateral hemisphere can provide insights into the underlying mechanisms of language function compensation in patients with gliomas. This study included 60 patients with eloquent-area or near-eloquent-area gliomas. The participants were grouped according to the degree of language defect. T1 and diffusion tensor imaging were obtained. The contralesional cortical volume and the subcortical network were compared between groups. Patients with unimpaired language function showed elevated cortical volume in the midline areas of the frontal and temporal lobes. In subcortical net

SUBMITTER: Zhou C 

PROVIDER: S-EPMC9496725 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature