Neural Activity Associated with Symptoms Change in Depressed Adolescents following Self-Processing Neurofeedback.

ABSTRACT: Adolescent depression is prevalent, debilitating, and associated with chronic lifetime mental health disorders. Understanding the neurobiology of depression is critical to developing novel treatments. We tested a neurofeedback protocol targeting emotional regulation and self-processing circuitry and examined brain activity associated with reduced symptom severity, as measured through self-report questionnaires, four hours after neurofeedback. Depressed (n = 34) and healthy (n = 19) adolescents participated in (i) a brief neurofeedback task that involves simultaneously viewing their own happy face, recalling a positive autobiographical memory, and increasing amygdala-hippocampal activity; (ii) a self- vs. other- face recognition task with happy, neutral, and sad facial express

SUBMITTER: Ahrweiler N 

PROVIDER: S-EPMC9496932 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature