Body Composition in Adolescent PKU Patients: Beyond Fat Mass.

ABSTRACT: There is a lack of evidence on the impact on body composition of high protein intake and types of protein substitutes in PKU patients-particularly in adolescents, who are more inclined to dietary transgressions. In this observational, cross-sectional study, PKU patients were observed during prepubertal age (p) or after the pubertal spurt (P), assessing body composition and bone quality and correlating these parameters with dietary compliance and types of protein substitutes. Anthropometric and dietary data were evaluated together with bioelectrical impedance analysis (BIA), quantitative ultrasound (QUS) and branched-chain amino acids (BCAAs). A total of 36 patients (16 males, 17 prepubertal and 19 post-pubertal; mean ± SD age 11.4 ± 3.9 years) were included. A higher BMI was observed in ad

SUBMITTER: Tummolo A 

PROVIDER: S-EPMC9497631 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature