Predictive Factors for Bilateral Disease in Papillary Microcarcinoma: A Retrospective Cohort Study.

ABSTRACT:

Background

Based on risk stratification, the therapeutic options in papillary microcarcinoma (PTMC) can be active surveillance or surgery. Multifocal tumor occurrence can be decisive in determining the treatment strategy. The objective of this study was to identify risk factors for bilateral tumor occurrence in PTMC to enable individual therapy planning.

Methods

A total of 545 PTMC patients who underwent thyroidectomy from 2008 to 2020 were retrieved. Univariate and multivariate analyses were performed to evaluate risk factors for bilateral PTMC.

Results

25.1% (n = 137) of all patients had multifocal PTMC, and 13.2% (n = 72) bilateral PTMC, respectively. In contrast to the maximum tumor size, the total tumor size significantly influenced a bilateral tumor manif

SUBMITTER: Lindner K 

PROVIDER: S-EPMC9497734 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature