Do the Causes of Spontaneous Preterm Delivery Affect Placental Inflammatory Pathology and Neonatal Outcomes?

ABSTRACT:

Objective

To investigate the severity of histologic chorioamnionitis /funisitis according to the indication for preterm delivery and their corresponding neonatal outcomes.

Method

This study included 411 singleton women who delivered between 21⁺⁰ and 31⁺⁶ week of gestation due to preterm labor (PTL, n = 165), preterm premature rupture of membranes (PPROM, n = 202), or incompetent internal os of the cervix (IIOC, n = 44). The primary outcome measure was the rate of severe histological chorioamnionitis/funisitis. Secondary outcome measure was neonatal outcomes including neonatal and infant death, and neonatal composite morbidity.

Results

The PPROM group demonstrated a higher rate of severe histological chorioamnionitis/funisitis

SUBMITTER: Jang IY 

PROVIDER: S-EPMC9498177 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature