A novel chitosan and polydopamine interlinked bioactive coating for metallic biomaterials.

ABSTRACT: Chitosan coatings have shown good bioactive properties such as antibacterial and antiplatelet properties, especially on blood-contacted biomedical materials. However, as blood-contacted biomedical device, the intravascular metal stent has a burden with adverse effects on the structural integrity, such as mechanical load during implantation and substrate degradation if a biodegradable metal is used as the substrate. It is unquestionably true that the structural integrity of the coated stent is essential. The adhesion strength between the coating and the substrate positively affects it. Silane and polydopamine (PDA) interstitial layers have been investigated to improve the corrosion resistance, biosafety and adhesion strength. This work addressed this challenge by using PDA as an intermediat

SUBMITTER: Eren ED 

PROVIDER: S-EPMC9499904 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature