Cell Rover-a miniaturized magnetostrictive antenna for wireless operation inside living cells.

ABSTRACT: An intracellular antenna can open up new horizons for fundamental and applied biology. Here, we introduce the Cell Rover, a magnetostrictive antenna which can operate wirelessly inside a living cell and is compatible with 3D biological systems. It is sub-mm in size, acoustically actuated by an AC magnetic field and resonantly operated at low MHz frequencies, which is ideal for living systems. We developed an injection scheme involving non-uniform magnetic fields for intracellular injection of the Cell Rovers and demonstrated their operation in fully opaque, stage VI Xenopus oocytes, for which real-time imaging with conventional technologies is challenging. We also show that they provide a pathway for multiplexing applications to individually address multiple cells or to tune to more than o

SUBMITTER: Joy B 

PROVIDER: S-EPMC9499948 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature