Effect of obstructive sleep apnoea syndrome and continuous positive airway pressure treatment on choroidal structure.

ABSTRACT:

Objectives

To evaluate the effect of obstructive sleep apnoea syndrome (OSAS) and continuous positive airway pressure (CPAP) therapy on choroidal structural changes and choroidal vascularity index (CVI) in patients with OSAS.

Methods

Choroidal structural changes in patients with OSAS immediately after diagnosis and 12 months after CPAP treatment were evaluated and compared with healthy controls. The choroidal images on enhanced depth imaging optical coherence tomography (EDI-OCT) were binarized into luminal area (LA) and stromal area (SA) using the ImageJ software. CVI was calculated as the ratio of LA to total choroid area (TCA). The correlations between the results of polysomnography (PSG) and choroidal parameters were evaluated.

Results

A total of 48 eyes of 48 pat

SUBMITTER: Altinel MG 

PROVIDER: S-EPMC9500031 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature