COL11A1 serves as a biomarker for poor prognosis and correlates with immune infiltration in breast cancer.

ABSTRACT: Breast cancer is the malignant tumor with the highest incidence rate at present, and its incidence rate ranks first in the female population. COL11A1 is an important component of collagen XI and is considered to play an important role in a variety of connective tissue diseases. Recent studies have shown that COL11A1 is associated with the occurrence and development of many kinds of malignant tumors. However, its prognostic value in breast cancer and its correlation with immune cell infiltration in tumor tissue are not clear. In this paper, we reveal the prognostic value of COL11A1 in breast cancer and its tumor immune-related function through in-depth bioinformatics analysis. The expression of COL11A1 is abnormally upregulated in breast cancer and is significantly related to the poor progn

SUBMITTER: Luo Q 

PROVIDER: S-EPMC9500398 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature