Optimizing estradiol level for gonadotrophin-releasing hormone antagonist initiation among patients with simple tubal factor infertility.

ABSTRACT:

Objective

The aim of this study is to investigate the optimal estradiol (E₂) level on the day of gonadotropin-releasing hormone antagonist (GnRH-ant) initiation to maximize the clinical pregnancy rate (CPR) after fresh embryo transfer among patients with simple tubal factor infertility.

Methods

A retrospective cohort study was conducted in the Reproductive Medicine Center, the Second Hospital of Hebei Medical University. A total of 1,493 IVF-ET cycles of patients diagnosed with single tubal factor infertility from August 2016 to August 2021 were included and equally allocated into five distinct groups according to the quintile serum E₂ levels on the day of GnRH-ant initiation. The five groups had similar baseline data except for antral follicle count.

SUBMITTER: Wang Y 

PROVIDER: S-EPMC9500406 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature