Comparison of Sodium-Glucose Cotransporter 2 Inhibitors vs Glucagonlike Peptide-1 Receptor Agonists and Incidence of Dry Eye Disease in Patients With Type 2 Diabetes in Taiwan.

ABSTRACT:

Importance

Sodium-glucose cotransporter 2 (SGLT2) inhibitors have been found to improve low-grade systemic and tissue inflammation; however, the association between SGLT2 inhibitor use and the incidence of dry eye disease (DED) has not been explored.

Objective

To investigate the association between SGLT2 inhibitor use and dry eye disease in patients with type 2 diabetes (T2D).

Design, setting, and participants

A retrospective cohort analysis of the largest multi-institutional electronic medical records database in Taiwan was conducted to identify patients with T2D newly receiving SGLT2 inhibitors or glucagonlike peptide-1 receptor agonists (GLP-1 RAs) from 2016 to 2018. Data analysis was performed from March 1 to May 31, 2022. Propensity scores with inverse probabilit

SUBMITTER: Su YC 

PROVIDER: S-EPMC9500553 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature